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Please use this identifier to cite or link to this item: http://hdl.handle.net/2307/256

Title: Assessment of novel chemical strategies for covalent attachment ofadhesive peptides to rough titanium surfaces: XPS analysis andbiological evaluation
Authors: Dettin, Monica
Herath, Thushari
Gambaretto, Roberta
Iucci, Giovanna
Battocchio, Chiara
Bagno, Andrea
Ghezzo, Francesca
Di Bello, Carlo
Polzonetti, Giovanni
Di Silvio, Lucy
Keywords: bone-implant internterface
extracellular-ilar-matrix
cell response
in-vitro
growth
Issue Date: Nov-2009
Publisher: WILEY-LISS
Abstract: Bioactive molecules have been proposed to promote beneficialinteractions at bone-implant interfaces for enhancing integration. Themain objective of this study was to develop novel methods tofunctionalize oxidized titanium surfaces by the covalent immobilizationof bioactive peptides, through selective reaction involving singlefunctional groups. In the first protocol, an aminoalkylsilane wascovalently linked to the Ti oxide layer, followed by covalent bindingof glutaric anhydride to the free NH2 g
...more
URI: http://hdl.handle.net/2307/256
ISSN: 1549-3296
DOI: 10.1002/jbm.a.32222
Appears in Collections:A - Articolo su rivista
Dipartimento di Fisica 'Edoardo Amaldi'

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