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Please use this identifier to cite or link to this item: http://hdl.handle.net/2307/609

Title: Analysis of Vγ9Vδ2 T lymphocytes response to human glioma cell lines: possible implications for therapy
Other Titles: Analisi della risposta dei linfociti T Vγ9Vδ2 a linee cellulari di glioma umano : possibili implicazioni per la terapia
Authors: Cimini, Eleonora
Tutor: Lauro, Giuliana Maria
Issue Date: 16-Feb-2009
Publisher: Università degli studi Roma Tre
Abstract: T cells link innate and acquired immunity. In humans 90% of circulating T cells express the V9V2 TCR rearrangement and recognize non peptidic antigens in a MHC-unrestricted manner. After antigen recognition, activated V9V2 T cells rapidly proliferate, produce high levels of cytokines and chemokines and can differentiate in cytotoxic effector cells. Specifically, V9V2 T cells recognize unprocessed non-peptidic compounds such as isopentenyl pyrophosphate (IPP), which are produced through
URI: http://hdl.handle.net/2307/609
Appears in Collections:X_Dipartimento di Biologia
T - Tesi di dottorato

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